Facilitation of Mount Behavior in Female Rats by Caudal Deefferentation of the Ventromedial Hypothalamus
نویسندگان
چکیده
2. Project Title: Conditional knock-out of GnRH neurons and its effects on development, emotionality and behavior in mice 3. Japanese Investigator ’s Name, Title, Affiliation and Phone Number: Chief : Yasuo Sakuma, Professor, Nippon Medical School, Tel: 03-3824-6640 Collaborators: Kunihiko Obata, Professor, National Institute for Physiological Sciences, Tel: 0564-55-7700 Masakatsu Kato, Associate Professor, Nippon Medical School, Tel: 03-3822-2131 Ishwar Parhar, Assistant Professor, Nippon Medical School, Tel: 03-3822-2131 Yasuhiko Kondo, Research Associate, Nippon Medical School, Tel: 03-3822-2131 Chitose Orikasa, Research Associate, Nippon Medical School, Tel: 03-3822-2131 Yukitoshi Nanasaki, Post Doctoral Fellow, Nippon Medical School, Tel: 03-3822-2131 4. U.S. Investigator ’s Name, Title, and Affiliation: Chief : Donald W. Pfaff, Professor, The Rockefeller University Collaborator: Sonoko Ogawa, Associate Professor, The Rockefeller University
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Effect of sulpiride injection into ventromedial nucleus of hypothalamus on food and water intake and weight in male rats
Weight gain, obesity and hyperprolactinemia are important complications of long-term administration of neuroleptic drugs, which may affect the patient's general health and well- being that itself interferes with treatment compliance. The purpose of this study was to identify the mechanism of occurrence of these side-effects. Because of the important role of ventromedial nucleus of hypothalamus ...
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The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...
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The ventromedial hypothalamus (VMH) plays a central role in the regulation of the female reproductive behavior lordosis, a behavior dependent upon the sequential activation of receptors for the ovarian steroid hormones estradiol (E) and progesterone (P). These receptors function as transcription factors to alter the expression of target genes. To discover behaviorally relevant genes targeted by...
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The ventrolateral hypothalamus (VLH) in female guinea pigs includes a subset of neurons which contain estrogen and progestin receptors, and which are implicated in the regulation of female sexual behavior by steroid hormones. However, little is known about where these neurons project, and consequently which other brain areas are involved in sexual behavior in female guinea pigs. The anterograde...
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